| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | ISEE | Common Stock | Options Exercise | $11.9K | +8.24K | +12.43% | $1.45* | 74.5K | Mar 18, 2022 | Direct | F1, F2 |
| transaction | ISEE | Common Stock | Sale | -$197K | -11.6K | -15.52% | $17.00 | 62.9K | Mar 18, 2022 | Direct | F1, F3 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | ISEE | Stock Option (right to buy) | Options Exercise | $0 | -8.24K | -8.24% | $0.00 | 91.8K | Mar 18, 2022 | Common Stock | 8.24K | $1.45 | Direct | F1, F4 |
| Id | Content |
|---|---|
| F1 | The exercises and sales reported on this form were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 19, 2021. |
| F2 | This total includes 764 shares acquired by the Reporting Person on March 15, 2022, under the Registrant's 2016 Employee Stock Purchase Plan that were not previously reported. |
| F3 | The sale price of the Reporting Person's shares represents the weighted average price of all shares sold by a broker in multiple transactions effected at prices ranging from $17.00 to $17.02 per share on March 18, 2022. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Registrant or a security holder of the Registrant, information regarding the number of shares sold at each price within the range. |
| F4 | This stock option award was granted on December 12, 2018 and vests with respect to 25% of the shares subject to the option on the first anniversary of the grant date and with respect to the remaining shares in approximately equal monthly installments through the fourth anniversary of the grant date. |