| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | ALNY | Common Stock | Options Exercise | $1.95M | +30.9K | +139.87% | $63.00 | 53K | Feb 10, 2023 | Direct | F1 |
| transaction | ALNY | Common Stock | Sale | -$364K | -1.71K | -3.22% | $213.13 | 51.3K | Feb 10, 2023 | Direct | F1, F2 |
| transaction | ALNY | Common Stock | Sale | -$494K | -2.31K | -4.5% | $214.28 | 49K | Feb 10, 2023 | Direct | F1, F3 |
| transaction | ALNY | Common Stock | Sale | -$2.22M | -10.3K | -20.98% | $215.59 | 38.7K | Feb 10, 2023 | Direct | F1, F4 |
| transaction | ALNY | Common Stock | Sale | -$4.21M | -19.4K | -50.23% | $216.38 | 19.3K | Feb 10, 2023 | Direct | F1, F5 |
| transaction | ALNY | Common Stock | Sale | -$934K | -4.3K | -22.32% | $217.05 | 15K | Feb 10, 2023 | Direct | F1, F6 |
| holding | ALNY | Common Stock | 515 | Feb 10, 2023 | by Managed Account | F7 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | ALNY | Stock Option (right to buy) | Options Exercise | $0 | -30.9K | -100% | $0.00* | 0 | Feb 10, 2023 | Common Stock | 30.9K | $63.00 | Direct | F1, F8 |
| Id | Content |
|---|---|
| F1 | All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 7, 2022. |
| F2 | The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $212.71 to $213.70. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range. |
| F3 | The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $213.72 to $214.66. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range. |
| F4 | The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $214.88 to $215.88. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range. |
| F5 | The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $215.89 to $216.89. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range. |
| F6 | The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $216.96 to $217.31. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range. |
| F7 | Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program. |
| F8 | The stock option vested as to 25% of the shares on the 1st anniversary of the date of the stock option grant and as to an additional 6.25% of the shares each successive three month period thereafter. |